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Ongoing Trials


 

Thank you for your interest in taking part in our ongoing trials.

 

 

At times Richmond Pharmacology may be involved in a number of different clinical trials involving healthy volunteers, patients and other specialised volunteer panels.

 


Are you a healthy South Asian male aged 18 to 55?

Have you ever wondered how new medicines are researched?

Be part of that development process

  • Who we are
Richmond Pharmacology conducts medical research to help develop new medicines and improve current treatments available to patients. We work closely with Hospital Consultants, Research Physicians, and Clinicians ensuring the research we carry out is meaningful, ethical, and safe. Our research unit, based at Croydon University Hospital in London, provides you with the safe and comfortable facilities.
  • What is this all about?
We are conducting a clinical research study of a new medicine being developed for slowing down the cell division and growth of cancer tumours. In this study we are testing the pharmacokinetics (PK) of the study medication (i.e. how it is distributed and broken down in the body) and pharmacodynamics (i.e. how effective it is) as well as the safety and tolerability in healthy male volunteers from different ethnic backgrounds including South Asian ethnic backgrounds. 

The trial is being conducted at Richmond Pharmacology Ltd only.
  • Who is suitable for this study?
To qualify for participation you need to be a healthy first generation Indian, Pakistani or Bangladeshi male aged between 18 and 55, inclusive, at screening.

By first generation we mean:
  • You were born in India, Pakistan or Bangladesh
  • BOTH your parents and grandparents (both maternal and paternal) were born in India, Pakistan or Bangladesh
  • You are in possession of a valid Indian, Pakistani or Bangladeshi passport
  • You have not lived outside your country of origin for longer than 5 years

You also need to be a non-smoker and or you have not been a smoker for a period of 3 months or more

Other restrictions and exclusions apply – please ask for details.
  • Study Participation
This study is being conducted at our research facility at Croydon University Hospital in London. If you are interested in taking part you will need to contact us to register your interest. You would need to first attend a screening visit within 28 days before the start of the study. This is to make sure you are medically suitable to take part in the study. This would be Visit 1.

If you are medically suitable following your screening visit and you are still interested in taking part in this study you must be prepared to attend our clinical trials unit for 1 residential visit lasting 4 days and 3 nights (Visit 2) and final follow-up visit 7 days after the lost dose of the study medication. Your participation in this study will last roughly 5 weeks.

Summary dates

Residential visit

Admission: Thursday, 8th May
Dismissal: Sunday, 11th May

Final follow-up visit:  Friday, 16th May

  • What do I receive if I decide to take part in this study?
Apart from helping medical research, you will also be paid for your time if you are included into the study.

You will receive £350 your time on completion of the study, once all results are confirmed, checked and deemed complete by the study doctor. You may be paid an additional payment of £180 as long as you meet the study requirements from start to finish, which include punctual attendance for appointments, being polite to staff and not bringing items into the clinical trials unit that you should not have with you at the time, such as other food and cigarettes. It should be noted that the bonus payment is at the discretion of Richmond Pharmacology Ltd. A full list of unit rules is available if you decide to attend a screening appointment.

The total amount that you could be paid for participation is £530. This includes all travel expenses.

  • Want to find out more?
If you are interested in finding out more Click here to register

Email volunteer@richmondpharmacology.com for details

Or

Call us on +44 (0)20 8664 5200 (choose option 1) and speak to a member of our Volunteer Recruitment Team.

A detailed information sheet is available on request.



Ref: AN1_APRIL 2014 (web story)

The contents of this web page have been approved by an ethics committee. Any response to this advertisement will be recorded.  Your response will not place you under any obligation to participate in this trial.


You may be required to remain resident in the unit until resolution of any safety issues, after which you will be discharged from the unit.


AD REF: C13052_web story_version 1.0_04.04.14



Register now for more details!


Do you have osteoarthritis of the knee?
Help us improve current treatments available to patients

  • Who we are

Richmond Pharmacology conducts medical research to help develop new medicines and improve current treatments available to patients. Our research unit, based at Croydon University Hospital in London, provides you with the safe and comfortable facilities.

  • What is this all about?

In this study we are testing the safety and tolerability of the study treatment, and whether it is effective as a treatment for pain relief when injected into the knee. This study treatment is currently under development and this is the first time it will be injected into the knee joint. Similar products have also been explored in studies for treatment of pain in osteoarthritis of the knee and other joints.

If you take part in the study, you will receive 1 injection into the knee joint (specifically, into the fluid that lines the knee joint space). You will be randomly assigned to receive either the study treatment or placebo. A placebo is just like the study treatment but it does not contain the active study ingredient.

The study is being conducted at Richmond Pharmacology Ltd only.

  • Who is suitable for this study?

We are looking for male or female volunteers, aged between 25 and 80, who have osteoarthritis of the knee confirmed at screening by osteoarthritis history, physical examination and x-ray.

Other restrictions and exclusions apply - please ask for details.

  • Study Participation

This study is being conducted at our research facility at Croydon University Hospital in London.

You will need to attend one or two screening visits before the start of the study. If you are medically suitable following your screening visit(s) and you are still interested in taking part in this study you will need to attend 4 visits to our clinical unit including 1 residential visit over 3 days (2 nights) and 3 outpatient visits. You will be involved in the study for approximately 10 weeks.

  • Summary study dates

Screening appointments will be held up to Tuesday,3rd June, inclusive.


Residential visit

Admission: Wednesday, 4th June

Dismissal: Friday, 6th June


Outpatient visits 


Visit 1: Thursday, 12th June

Visit 2: Thursday, 26th June

Visit 3 (Follow-up visit): Thursday, 17th July

  • What do I receive if I decide to take part in this study?

Apart from helping medical research, you will also be paid for your time if you are included into the study.

All payments are based purely on the duration of the study and expenses incurred and not on the inconveniences or risks involved. In recognition of the time involved in taking part in this study, you will be paid £480 on completion of the study, once follow-up results are confirmed, checked and deemed satisfactory by the Research Doctor. This payment includes all travel expenses.

You may be paid a bonus of £240 subject to your satisfactory compliance with this document (Subject Information/Informed Consent Form), the Richmond Pharmacology Volunteer Charter and all unit rules (unit regulations). However, the bonus payment is issued at the discretion of RPL, meaning RPL is not in any way obliged to pay these monies under the terms of the contract with the volunteers. The total amount that you could be paid is £720. If you are involved in the extended phase of the study, you will receive £100 per additional visit you attend.

  • Want to find out more?

If you are interested in finding out more select the I am interested link below to arrange a call back

Or


Email oaknee@richmondpharmacology.com  to request a detailed information sheet.

Ref: BA 3_OCTOBER (web story)

The contents of this email have been approved by an ethics committee. Any response to this advertisement will be recorded. Your response will not place you under any obligation to participate in this trial.

You may be required to remain resident in the unit until resolution of any safety issues, after which you will be discharged from the unit.

C13055_web story_version 2.0_19.11.13_


Register now for more details!


Do you have atopic dermatitis (eczema) which affects between 5 and 20% of your body's surface area?

 ***** This study has now come to an end however we may have similar trial opportunities coming up in the future. Please register via our online registration form and we will keep you posted on upcoming trials that you may be suitable for. *****


Have you ever wondered how new medicines are researched?

Be part of that development process

  • Who we are
Richmond Pharmacology conducts medical research to help develop new medicines and improve current treatments available to patients. Our research unit, based at Croydon University Hospital in London, provides you with the safe and comfortable facilities.
  • What is this all about?

The purpose of this research study is to learn about the effects of a potential new topical medication on atopic dermatitis and its' itch.

This new drug has been designed to be applied to the skin and to work on selected enzymes (kinases) in the skin, which are reported to play a role in atopic dermatitis (TrkA).  It is believed that blocking the activity of such enzymes may improve the symptoms of atopic dermatitis and reduce itching.

Two different strengths of the study ointment (0.05% w/w and 0.5% w/w) will be tested and compared to a placebo to find out which is better for treating atopic dermatitis.  The placebo ointment looks the same as the active ointment but does not contain any drug.  This is a new investigational medication which is currently not approved for sale in the UK.

Because this is a research study, study medication will be given to you only during this study and will not be available at the end of the study.

The trial is being conducted at a number of locations including Richmond Pharmacology Ltd.

  • Who is suitable for this study?
To qualify for participation you need to:
  • have atopic dermatitis which affects between 5 and 20% of your body's surface area and is itchy.
Other restrictions and exclusions apply – please ask for details.
  • Study Participation

You would need to first attend a screening visit at our clinical trials unit in Croydon University Hospital up to 21 days before the start of the study. This is to make sure you are medically suitable to take part in the study. This would be Visit 1.

You will need to visit the research site at least 7 times during the study.  Screening tests will be carried out up to 21 days before the start of study treatment and may involve 1 or more visits to the site.  Screening will be followed by treatment for up to 4 weeks, during which time you will need to visit the clinic for assessments on Days 1, 4, 11, 17 and 29 of the treatment.  You will need attend a follow up visit approximately 14 days after stopping study treatment.  Therefore the longest that you are likely to be involved in the study is 9 weeks.

If you take part in the study, you will be assigned by chance (like the toss of a coin) to receive either 0.05% ointment, 0.5% ointment or placebo ointment.  You will have a 2 in 3 (66%) chance of receiving one of the active ointments and a 33% (1 in 3) chance of receiving placebo ointment.

This is a double-blind study, which means neither you nor the study team will know which treatment you are using.  This is done to make sure that the results of the study cannot be unfairly influenced by anyone.  However, in an emergency the study team can get this information quickly.

  • What do I get if I decide to take part in this study?

Apart from helping medical research, you will also be paid for your time if you are included into the study.

You will be reimbursed £30 for each study clinic visit that you attend, to cover your time as a result of your participation in this study.  If you leave the study early, for any reason, you will only be paid £30 for each study visit that you have already completed. Travel related to your attendance for study clinic visits will be reimbursed by Richmond Pharmacology.

  • Want to find out more?


If you are interested in finding out more Click here to register

Email itch@richmondpharmacology.com for details


Or

Call us on +44 (0)20 8664 5200 (choose option 1) and speak to a member of our Volunteer Recruitment Team.

A detailed information sheet is available on request.

Ref: Cre 6_JUN 2013


The contents of this web page have been approved by an ethics committee. Any response to this advertisement will be recorded.  Your response will not place you under any obligation to participate in this trial.

You may be required to remain resident in the unit until resolution of any safety issues, after which you will be discharged from the unit.


 AD REF: C13010_email text_version 1.0_06.06.13


Register now for more details!


Are you a healthy male or female aged 18 to 45?

Have you ever wondered how new medicines are researched?

Be part of that development process

  • What is this all about?

We are conducting a clinical research study with a medicine which is being developed for the treatment of very rare diseases related to the immune system as the current treatments are limited due to availability and costs.

The results from this study will help us to determine whether the study medication is a safe and effective medicine for these rare immune diseases and to design further clinical trials. It will also help us to decide the most effective dose and the most convenient way to administer the study medication to patients.

The trial is being conducted at Richmond Pharmacology Ltd only.

  • Who is suitable for this study?

To qualify for participation:

  • Be a non-smoking healthy male or female, aged between 18 and 45, inclusive, at screening.

  • If you are a female volunteer, you must be of non-childbearing potential; either surgically sterilised or post-menopausal (you have not had menstrual periods for at least 1 year and confirmed by FSH > 25IU/mL).

  • Have a body mass index (BMI) between ≥18.5 and ≤30.0 kg/m2 (inclusive) at screening. You can use this link to calculate your BMI

  • Be willing to use acceptable contraceptive methods, avoid unprotected sex, and donating eggs or sperm until 3 months after treatment.

Other restrictions and exclusions apply - please ask for details.

  • Study Participation

This study is being conducted at our research facility at Croydon University Hospital in London. If you are interested in taking part you will need to contact us to register your interest.

You will need to attend one screening visit up to 10 weeks before the dose of the study medication.

If suitable, you will be vaccinated against meningitis and pneumonia before you are given the study medication. You will be vaccinated at least eight weeks prior to administration of the study drug hence the long run in period.

If you are medically suitable following your screening visit and vaccinations, you will be required to stay at our Research unit for 1 in-house period of 5 days and 4 nights during which you will receive a single dose of the study medication.
After this you will need to attend 6 outpatient visits. The in-house stay and follow-up periods may be extended if necessary for your safety.

You will be involved in the study for up to 20 weeks.

Study Dates - Group 4

Screening appointments will be held every week day Monday through to Friday with the admission for this study due to start 2nd June 2014.

Summary Dates

1st vaccinations: To be confirmed once screening is completed
2nd vaccinations: 4 weeks after first vaccination

Admission:
Monday, 2 JUNE
Dismissal:
Friday, 6 JUNE

Outpatient visits:

Day 8:
Tuesday, 10 JUNE
Day 15:
Tuesday, 17 JUNE
Day 29:
Tuesday, 1 JULY
Day 43:
Tuesday, 15 JULY
Day 57:
Wednesday, 29 JULY

Follow-up:
Wednesday, 12 AUGUST

Please ask a member of our Volunteer Recruitment Team for full details.

  • What do I get if I decide to take part in this study?

Apart from helping medical research, you will also be paid for your time if you are included into the study.

Please note that payments will be made on a pro rata basis through the duration of the study. Please ask a member of the team for more details.

All payments are based purely on the duration of the study and expenses incurred and not on the inconveniences or risks involved. In recognition of the time and effort involved in taking part in this study, you will be paid £1,170 on completion of the study, once follow-up results are confirmed, checked and deemed satisfactory by the Research Doctor. This payment includes all travel expenses.

You may be paid a bonus of £580 subject to your satisfactory compliance with this document (Subject Information/Informed Consent Form), the Richmond Pharmacology Volunteer Charter and all unit rules (unit regulations). However, the bonus payment is issued at the discretion of RPL, meaning RPL is not in any way obliged to pay these monies under the terms of the contract with the volunteers.

The total amount that you could be paid for completion of the full study is £1,750.

If we ask you to come for a rescreening visit or the vaccinations are split over 2 visits, we will pay £40 for each additional visit.

To receive each of these payments you will need to have complied with the study requirements. If we withdraw you from the study, you may receive a pro-rata sum if certain conditions are met. These payment rates only apply to volunteers who have been included into the study i.e. have received a dose on Day 1.


All final study payments due to you will be paid 21 working days after your final follow-up visit


  • Want to find out more?
If you are interested in finding out more Click here to register

Email volunteer@richmondpharmacology.com for details

Or

Call us on +44 (0)20 8664 5200 (choose option 1) and speak to a member of our Volunteer Recruitment Team.

A detailed information sheet is available on request.



Ref: SI1_SEPTEMEBR 2013 (email text)

The contents of this web page have been approved by an ethics committee. Any response to this advertisement will be recorded.  Your response will not place you under any obligation to participate in this trial.


You may be required to remain resident in the unit until resolution of any safety issues, after which you will be discharged from the unit.


AD REF: C13031_web story_version 2.0_29.11.13


Register now for more details!


Do you have noticeable frown lines and/or crow’s feet?
Take part in a clinical trial & receive up to £720 for your time

Have you ever wondered how new medicines are researched?

Be part of that development process

  • Who we are

Richmond Pharmacology conducts medical research to help develop new medicines and improve current treatments available to patients. Our research unit, based at Croydon University Hospital in London, provides you with the safest and most comfortable facilities.

  • What is this all about?

We are conducting a medical research study of a new treatment being developed to improve the appearance of frown lines (wrinkles that appear between the eyebrows) and crow's feet (wrinkles around the outer edeges of the eyes). As a person ages, the skin becomes less elastic and these wrinkles become more pronounced. In some cases, they stay on the face permanently, making it appear that the person is always frowning or angry. Hence wrinkle treatments can make a difference to a person's self-perception, emotional wellbeing, and how others perceive them on first impression.

In this study we are testing the safety and tolerabilityof the study treatment and how effective it is (i.e. whether a temporary improvement in these wrinkles can be seen) when given at different dose levels. Similar licensed products such as Vistabel®, Azzalure® and Bocouture® have been used extensively for the treatment of these wrinkles, and are considered to be safe and effective.

You may not receive any benefits from receiving the study treatment as it is being given purely for research and development purposes.

The trial is being conducted at Richmond Pharmacology Ltd only.

  • Who is suitable for this study?
To qualify for participation you need to:

Be a healthy male or female of any race, 18 to 65 years of age (inclusive) at screening.

You are in good health in relation to your age as determined by medical history, physical examination or other evaluations conducted at screening or on admission.

You have not previously received treatment with BoNT-A or B products (commonly known as Botox injections).

You have a skin wrinkle severity score, at maximum frown (GL) or maximum smile (LCL), of at least moderate severity (grade 2) as assessed by the Research Doctor at the screening and baseline visits using the validated photo scales.

You have a skin wrinkle severity score, at rest, of at least mild severity (grade 1) as assessed by the Investigator at the screening and baseline visits using a validated photo scale - at rest.

You have not undergone prior facial cosmetic surgery (e.g., blepharoplasty, periorbital surgery, facial lift, brow lift, eyelid lift or eyebrow surgery).

You must agree to use acceptable methods of contraception.

Other restrictions and exclusions apply – please ask for details.

  • Study Participation
You would need to first attend a screening visit at our clinical trials unit in Croydon University Hospital within 28 days before the start of the study. This is to make sure you are medically suitable to take part in the study. This would be Visit 1.

If you are medically suitable following your screening visit and you are still interested in taking part in this study you must be prepared to attend our clinical trials unit for 1 residential visit lasting 3 days and 2 nights, or 2 days and 1 night (this would be Visit 2). If you take part in the study, you will receive 5 intramuscular (injection into your facial muscles) injections or placebo (‘dummy drug’) for GL or 3 injections on each side of your upper face for LCL or you may receive a combination of GL and LCL injections. You will need to attend a further 4 out-patient visits (Visits 3-6) and a final follow-up visit 28 days after the study treatment has been given (Visit 7). Your participation in this study will last roughly 8 weeks.

Study dates (Group 6)

Admission:
Tuesday, 8 APRIL
Dismissal:
Thursday, 10 APRIL

Outpatient visits:

Friday, 11 APRIL
Tuesday, 15 APRIL
Tuesday, 22 APRIL
Tuesday, 29 APRIL

Follow-up:
Tuesday, 6 MAY
  • What do I get if I decide to take part in this study?

Apart from helping medical research, you will also be paid for your time if you are included into the study.

If you are included in the first and sentinel groups of the study, you will receive £480 your time on completion of the study, once all results are confirmed, checked and deemed complete by the study doctor. You may be paid an additional payment of £240 as long as you meet the study requirements from start to finish, which include punctual attendance for appointments, being polite to staff and not bringing items into the clinical trials unit that you should not have with you at the time, such as other food and cigarettes. It should be noted that the bonus payment is at the discretion of Richmond Pharmacology Ltd. A full list of unit rules is available if you decide to attend a screening appointment.

If you are included in the remaining groups of the study, you will receive £470 your time on completion of the study, once all results are confirmed, checked and deemed complete by the study doctor. You may be paid an additional payment of £230 as long as you meet the study requirements from start to finish, as mentioned above.

  • Want to find out more?
If you are interested in finding out more Click here to register

Email wrinklestudy@richmondpharmacology.com for details

Or

Call us on +44 (0)20 8664 5200 (choose option 1) and speak to a member of our Volunteer Recruitment Team.

A detailed information sheet is available on request.



Ref: BA 1_Aug 2013 (email text / web story)


The contents of this email have been approved by an ethics committee. Any response to this advertisement will be recorded.  Your response will not place you under any obligation to participate in this trial.

You may be required to remain resident in the unit until resolution of any safety issues, after which you will be discharged from the unit.



AD REF: C11098_email text_version 2.0_15.08.13 | C11098_web story_version 1.0_25.03.13




Register now for more details!

 

Healthy Volunteer Trials

 

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