Paid clinical trial for healthy volunteers aged 18 to 45.
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We are carrying out a clinical trial in healthy volunteers with an investigational drug being developed for the treatment of Malaria. The results from this clinical trial will help to work out if this drug can be developed further for testing in patients with Malaria.

Register your interest in this clinical trial

Study summary

Single Ascending Dose (SAD) Cohort (Part A)

This study will be carried out at our clinical trials unit in London Bridge and requires an estimated time commitment of up to 6 weeks. Participation will involve one or more screening visits to determine your suitability. If you are included in the study, you will be required to be in our unit for one in house stay of 4 nights /5 days and 4 out-patient/ follow up visits. Please refer to the calendar for the proposed study dates.

Food Effect (FE) Cohort (Part B)

This study will be carried out at our clinical trials unit in London Bridge and requires an estimated time commitment of approximately 8 weeks. Participation will involve one or more screening visits to determine your suitability. If you are included in this study, you will be required to attend two periods of one in house stay of 4 nights /5 days and one follow up visit after each in-house period. Please refer to the calendar for the proposed study dates.

Study dates

Food Effect (FE) Cohort (Part B)

Period 1:

  • Screening period: November 6th-November 21st (only 1x screening appointment required)
  • In-house period: November 23rd-27th
  • Outpatient visit: November 29th

Period 2:

  • In-house period: December 7th-11th
  • Outpatient visit: December 13th

Single Ascending Dose (SAD) Cohort (Part A)

  • Screening period: November 10th-November 28th (only 1x screening appointment required)
  • In-house period: November 30th-December 4th
  • Outpatient visit: December 6th


Who can take part?

To be eligible to take part in this study you must fit the following criteria:

  • Male aged 18 to 45 (inclusive)
  • Female aged 18 to 45 of non-childbearing potential. Non-childbearing potential is either (spontaneous) post-menopausal for at least 12 months or pre-menopausal with irreversible surgical sterilization for at least 6 months.
  • You must weigh at least 50kg and have a Body Mass Index (BMI) within the range of 18 and 25 kg/m2(inclusive)
  • You must be healthy with no relevant history of illness or ongoing medical conditions which could interfere with participation in the clinical study
  • You must be a non smoker or a light smoker (5 or less cigarettes a day). Volunteers must be able to abstain from smoking while in the unit.
  • You must consume less than 21 units (males), 14 units (females) of alcohol per week
  • You must not have donated more than 500ml of blood within 90 days
  • You must not test positive for drug or alcohol abuse, pregnancy, hepatitis B/C or HIV.
  • You must not have used any medication or dietary supplements within 7 days of being given the study medication (except paracetamol)
  • You must not have used any herbal supplements within 30 days of being given the study medication
  • Male subjects must agree to use acceptable methods of contraception with their female partner from the time of the first administration of study medication until 100 days

Effective contraceptive methods (for partners) and a full list of medical eligibility requirements will be discussed in detail with the study doctor during screening.
 
Study payment

Single Ascending Dose (SAD) Cohort (Part A)
In recognition of the time involved in taking part in this study, you will receive £1,030 on completion of the study, provided you comply fully with all the study requirements.

Food Effect (FE) Cohort (Part B)
In recognition of the time involved in taking part in this study, you will receive £1,655 on completion of the study, provided you comply fully with all the study requirements.

This amount is based on the anticipated study plan and will be adjusted pro-rata (i.e. same amount of money paid per unit of time), should we invite you to attend extra visits.

Get in touch
Call our team for more information: +44 (0) 20 7042 5800 (opt 1)
We are open weekdays 9am-5pm
or email us: volunteer@richmondpharmacology.com

Ref: MMV_November 2017 (email_website_advert text)

The contents of this page have been approved by an ethics committee. Any response to this advertisement will be recorded. Your response will not place you under any obligation to participate in this trial.

You may be required to remain resident in the unit until resolution of any safety issues, after which you will be discharged from the unit.

Register your interest in this clinical trial