Receive £2,016 in recognition of the time involved
We are conducting a clinical trial in healthy male and female volunteers for a new medicine that could be used to treat people with malaria, or prevent malaria, more cost-effectively compared to an existing medicine. You will be paid for your time if you take part in this clinical trial.
Clinical trial summary
In this clinical trial, we are asking up to 16 healthy male and female participants aged 18 to 55 to test an experimental (not yet marketed) medicine compared to a marketed medicine, which is intended to be used to treat people with malaria or prevent malaria, so we can measure the levels of breakdown products in the blood and how long they stay in your body.
The trial will involve you staying with us for two periods of 5 days / 4 nights (see below) at our private medical facility in London Bridge.
During your stay, we will conduct safety assessments and collect blood and urine samples to assess the new medicine.Register for this clinical trial
If you are interested in participating in the trial:-
- You will need to attend a screening appointment so we can check if you are suitable to take part in the trial. At this appointment we perform a number of tests including, taking blood, checking your heart, and carrying out a physical examination to see if you will be OK to take part in the clinical trial.
- If results from your screening appointment show you are suitable for the trial, you will be invited to take part.
- This will involve two treatment periods of 5 days / 4 nights each when you will stay in our clinical research unit. i.e. Treatment Periods 1 and 2. The dosing day of each treatment period will be separated by at least 24 days to ensure the medicine has left your body prior to the next dose being given in Treatment Period 2.
- After your stay with us, you will be required to return for further appointments on Day 8, Day 15, and Day 22 in Treatment Periods 1 and 2. This means the whole study takes approximately 11 weeks from your screening visit through to your final visit.
- In total, if you are included in the clinical trial you will come to the research unit 9 times.
- During your stay with us, you will receive a single dose of the new medicine via tablets taken by mouth in Treatment Period 1 and a single dose of the marketed medicine via tablets taken by mouth in Treatment Period 2, or vice versa. We will conduct a number of assessments (like those we did at screening) to check how well you tolerate the new medicine and also measure the levels of the breakdown products in your blood to help us understand how long it takes for your body to get rid of the new medicine as compared to the marketed medicine.
Register your interest in this clinical trial
Clinical trial dates
Who can take part?
We will check your suitability for the clinical trial using the following criteria:-
- You are a male or female aged between 18 to 55 years inclusive.
- You must have a bodyweight of 50 to 80 kg and your Body Mass Index (BMI) is between 18.0 and 25.0 kg/m2, inclusive.
- You must be healthy with no underlying medical conditions that may affect the trial or put you at any significant risk.
- You must not test positive for alcohol or show any evidence of alcohol abuse.
- You must not test positive for drugs or show any evidence of drug abuse.
- You must not use prescription drugs within 14 days prior to the investigational medicine administration.
- Female participants of childbearing potential, if heterosexually active, must agree to the use of highly effective contraception starting from one complete menstrual cycle prior to the first dose until the follow-up visit.
- Male participants must be willing to use appropriate barrier contraception starting from the first day of dosing until the follow-up, with female partners of child-bearing potential, including partners that are already pregnant.
- Female participants must not be pregnant or breastfeeding.
- You must be a non-smoker (fewer than 100 lifetime cigarettes and zero cigarettes in the past 6 months).
- You must not have had a COVID-19 vaccine 4 weeks prior to the first dose or plan to receive the vaccine before the follow-up visit.
A full list of do’s and don’ts will be given to you by a member of our recruitment team if you are interested and want to find out more.
Clinical trial Payment
In recognition of the time involved in taking part in the trial, you will receive £2,016 (£1,356 clinical trial payment and £660 compliance payment) on completion of the clinical trial, provided you comply fully with all the clinical trial requirements. This amount is based on the anticipated clinical trial plan and will be adjusted pro-rata (i.e. same amount of money paid per unit of time), should we invite you to attend extra visits.
Contact our Volunteer Recruitment team
For more information call +44 (0) 20 7042 5800 or email: email@example.comRegister your interest in this clinical trial
You may be required to remain resident in the unit until the resolution of any safety issues, after which you will be discharged from the unit.
The contents of this page have been approved by an ethics committee. Any response to this advertisement will be recorded. Your response will not place you under any obligation to participate in this trial.
Ref: C19034_MAR_2021 (email_website_advert text)