Paid clinical trial for male and female volunteers with high blood pressure aged 18-65

Receive £3,970 for your time

We invite you to consider taking part in a clinical trial of an investigational drug (ALN-AGT01) being developed for the treatment of high blood pressure.

The main purpose of this study is to look at the safety of the drug and how well you tolerate it.

Study summary

This Phase 1 study will be conducted at our clinical trials unit in London Bridge. The study has 3 parts: screening, treatment, and follow-up.

Male and female mixed

Register your interest in this clinical trial

[Part B]

Screening period: To determine your eligibility for study participation, you would attend a
screening appointment. If you meet the initial eligibility, you will then have an in-house stay
of 14 days (option 1) or 7 days in-house stay with an option of staying 14 days to avoid daily
travel (option 2).
Treatment period: If you are eligible for study participation, then you will have 1 in-house
stay of 3 days / 2 nights. You will receive 1 dose of the study drug.
Follow-Up period: You will be required to be in our unit after receiving the dose of the study
drug as follows:
1 in-house stay of 14 days (option 1) or 7 days in-house stay with an option of staying
14 days to avoid daily travel (option 2), 43 days after receiving the study drug.
8 follow-up visits (every week) over a period of 3 months.
You may be required to attend additional follow-up visits every 84 days, if deemed
necessary by the Research Doctor. During this time, female participants will also be
seen every 30 days to test for pregnancy.

Study dates

C18038 Part B Cohort 1a

November 2020
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December 2020
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January 2021
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February 2021
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March 2021
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In House Period
Follow Up Appointment

 

Who can take part?

To be eligible to take part in this study you must fit the following criteria:

1. Be aged 18 to 65 years old.
2. Have a Body Mass Index (BMI) between 18.0-35.0, inclusive.
3. Have been diagnosed with high blood pressure and are taking medication for your high blood pressure and have had no changes to the medication in the 30 days prior to screening for this study

4. Be a non-smoker
5. Not test positive for alcohol
6. Not be pregnant, breast-feeding, nor planning to become pregnant during the study.
7. Female volunteers of childbearing potential must agree to the use of highly effective contraception starting 14 days prior to receiving the study drug and continuing until study completion.

A full list of acceptable contraceptive methods will be discussed in full by a member of the recruitment team and a study doctor during screening.

Study payment

In recognition of the time involved in taking part in this study, you will receive £3970 (£1323 bonus and £2647 study payment)  on completion of the study provided you comply fully with all the study requirements.

Get in touch
Call our team for more information: +44 (0) 20 7042 5800 (opt 1)
We are open weekdays 9am-5pm
or email us: volunteer@richmondpharmacology.com

Ref: C18038_Feb 2019 (email_website_advert text)

The contents of this page have been approved by an ethics committee. Any response to this advertisement will be recorded. Your response will not place you under any obligation to participate in this trial.

You may be required to remain resident in the unit until resolution of any safety issues, after which you will be discharged from the unit.

Register your interest in this clinical trial