Receive a study payment of £1,534
We are conducting a clinical trial for a potential new medicine that could be used to treat patients with non-alcoholic steatohepatitis (NASH) which is a form of non-alcoholic fatty liver disease. In this trial, we are asking healthy male and female volunteers aged 18 to 65 years to test the investigational medicine so we can see how well tolerated the medicine is and how long it stays in your body.
You will be paid for your time if you take part in this clinical trial.
If you are interested in participating in the trial:-
- This clinical trial will involve you staying with us for a few days (see below) at our private clinical research unit in London Bridge.
• You will need to attend a screening appointment so we can check if you are suitable to take part in the trial. At this appointment we perform a number of tests including, taking blood, checking your heart and carrying out a physical examination to see if you will be OK to take part in the clinical trial.
• If results from your screening appointment show you are a suitable for the trial, you will be invited to take part.
o This will involve a stay of 4 days / 3 nights in our clinical research unit.
o After your stay with us you will be required to return for further appointments on Day 15, Day 29, Day 43, Day 57 and Day 85 of the trial. This means the whole trial takes approximately 5 and a half months from your screening visit through to your final visit.
o In total, if you are included in the clinical trial you will come to the research unit 7 times.
• During your stay with us you will receive a single dose of the investigational medicine subcutaneously (i.e. injection just under the skin) and we will conduct a number of assessments (like those we did at screening) to check how well you tolerate the new medicine and to help us understand how long it takes for your body to get rid of the new medicine.
Register your interest in this clinical trial
*Only 1x screening appointment required
Who can take part?
We will check your suitability for the clinical trial using the following criteria:-
- • You are a male or female aged between 18 to 65 years inclusive.
• You have a Body Mass Index (BMI) within the range of 18.0 and 30.0 kg/m2.
• You must be healthy with no underlying medical conditions that may affect the trial or put you at any significant risk.
• You must not test positive for alcohol or show any evidence of alcohol abuse for 3 months during the past year prior to screening.
• You must not test positive for drugs or show any evidence of drug abuse 12 months prior to screening.
• You must not use prescription drugs within 14 days prior to screening.
• Female participants of childbearing potential, if heterosexually active, must agree to the use of highly effective contraception starting 14 days before the first dose and until study completion.
• Male participants must be willing to use appropriate barrier contraception for 5 days after each dose with female partners of child-bearing potential, including partners that are already pregnant.
• Female participants must not be pregnant or breastfeeding.
• You must not have other forms of known chronic liver disease.
• You must not have an intolerance to subcutaneous injection(s) or significant abdominal scarring that could potentially hinder the investigational medicine administration or evaluation of the investigational medicine administration site.
A full list of acceptable contraceptive methods will be discussed in full by a member of the recruitment team and a trial doctor during screening.
Clinical trial Payment
In recognition of the time involved in taking part in this study, you will receive £1,534 (£1,023 clinical trial payment and £511 bonus) on completion of the study provided you comply fully with all the study requirements. This amount is based on the anticipated study plan and will be adjusted pro-rata (i.e. same amount of money paid per unit of time), should we invite you to attend extra visits.
Contact our Volunteer Recruitment team
For more information call +44 (0) 20 7042 5800 or email:Register your interest in this clinical trial
You may be required to remain resident in the unit until resolution of any safety issues, after which you will be discharged from the unit.
The contents of this page have been approved by an ethics committee. Any response to this advertisement will be recorded. Your response will not place you under any obligation to participate in this trial.
Ref: C20017_Sep2019 (email_website_advert text)