0800 085 6464 - 9:00am to 5:00pm - Mon to Fri
Duration of stay
1 in-house stay in our unit of 5 days / 4 nights and 1 follow-up visit
London Bridge
Males & Females
Smoking Restrictions
Trial Code
Paid on completion of the study.
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We are looking for Caucasian men and women with type 2 diabetes aged 18 to 65 years to test a potential (i.e. investigational) medicine to treat type 2 diabetes.

This trial will involve you staying with us for a few days (see below) at our private medical facility in London Bridge.

Clinical trial summary

This trial will involve you staying with us for a few days (see below) at our private medical facility in London Bridge.

  • The investigational medicine works by binding certain hormones which are produced after eating a meal, causing a decrease in blood sugar levels.
  • The aim of this trial is to determine how safe and well tolerated the investigational medicine is when given to patients with type 2 diabetes.
  • The trial will also assess how long the investigational medicine remains in the blood and how it affects the body.
  • You will need to attend a screening appointment so we can determine if you are suitable to take part in the trial.
  • If your screening visit results show you to are a good candidate for the trial you will be invited to take part and this will involve 1 in-house stay in our unit of 5 days / 4 nights.
  • During your stay with us you will receive a single dose of the investigational medicine and we will conduct a number of assessments to check your safety and to help us understand how your body processes the drug.
  • After your stay with us you will return for 1 follow-up visit 11 days after you are discharged from the unit.
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Who can take part?

  • You are a Caucasian male or female.
  • You have type 2 diabetes and are aged between 18 to 65 years. You have a Body Mass Index (BMI) within the range of 18.0 and 35.0 kg/m2.
  • Your type 2 diabetes is treated with either:
Diet and exercise alone, or
A medication used to treat type 2 diabetes
Metformin (brand names include Glucophage and Fortamet),
A DPP-4 inhibitor/gliptin such as sitagliptin or linagliptin (brand names include Januvia and Trajenta),
Pioglitazone (brand names include Actos and Glidipion),
A sulphonylurea such as gliclazide or glibenclamide (brand names include Diamicron and Diabeta),
An SGLT-2 inhibitor/gliflozin such as dapagliflozin or empagliflozin (brand names include Forxiga and Jardiance).
  • You must be able to pause (washout) the medication you take (if you take any) to treat type 2 diabetes (above), to allow it to fully leave your system, prior to admission into the unit and for the duration of the trial.
  • You must not have been treated with two blood-sugar lowering therapies, exenatide (Bydureon), dulaglutide (Trulicity), liraglutide (Victoza) or lixisenatide (Lixumia), in the 3 months prior to dosing.
  • You must not have recently been in hospital due to low blood sugar (hypoglycaemia) or high blood sugar (hyperglycaemia) in the 3 months prior to dosing or Day -2.
  • You must not have any complications of diabetes such as poor kidney function or eye disease, any other chronic illness or condition or psychiatric illness that could affect the results of the clinical trial.
  • You must not consume tobacco in any form (e.g. smoking or chewing) or other nicotine-containing products (e.g. gum, patch, electronic cigarettes) 28 days prior to the planned admission (Day -2).
  • You must not be pregnant or breastfeeding.
  • Females: You must be willing to use appropriate contraception, starting from one complete menstrual cycle prior to the first day of dosing until the follow-up visit.
  • Males: You must be willing to use appropriate contraception, starting from the first day of dosing until the follow-up visit.

A full list of acceptable contraceptive methods will be discussed in full by a member of the recruitment team and a trial doctor during screening.

Clinical trial payment

In recognition of the time involved in taking part in this trial, you will receive £948 (£630 study payment and £318 bonus) on completion of the study provided you comply fully with all the trial requirements. This amount is based on the anticipated trial plan and will be adjusted pro-rata (i.e. same amount of money paid per unit of time), should we invite you to attend extra visits.

Clinical trial dates

  • In-House Period: 22nd to 26th February
  • Follow up Call: 6th March

You may be required to remain resident in the unit until the resolution of any safety issues, after which you will be discharged from the unit.

The contents of this page have been approved by an ethics committee. Any response to this advertisement will be recorded. Your response will not place you under any obligation to participate in this trial.

Ref: C19040_Jun2020

Register for this trial
If you would like to speak to a member of our Volunteer Recruitment Team, call us on 0800 085 6464
Register for this clinical trial

Contact our Volunteer Recruitment Team

Ref: (C19040) - (email_website_advert text)

Hear from some of our previous volunteers

“It’s like being part of a huge family gathering at Trials4us - even the cousin you don’t know very well goes out of their way to make you feel comfortable! Super professional as well as personable. 10/10”

Jonjo - November 2021

“Trials4us has been very informative and answered all of my questions and queries. The care has also been great, I have not had to worry, all the information has been very clear. They are very helpful and respond quickly”

Alex - June 2021

''I would like to thank Dr James Mitchell for always taking the time to answer any questions I have, no matter how small they are. He is very informed about my condition which is a novelty for me as my condition is very rare. His understanding has been a major influence in my participation of the trial''

James - December 2020

''I'm honestly very pleased with my experience with Trials4us. They were very helpful, and transparent about every step. I would definitely recommend them. 10/10 experience. Daniel and Omari, were especially nice and helpful. Thank you''

Mohamed - June 2020

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