Alpha-1 Antitrypsin Deficiency Study Group

If you have been diagnosed with Alpha-1, we would like to hear from you.

Alpha-1 Antitrypsin Deficiency (AATD) can be a debilitating hereditary disease. Many people wait years for a proper diagnosis and treatment options are limited.

But clinical research is entering a new era and today a diagnosis of AATD can give you access to trials of next generation treatments. The science is accelerating and you could be part of this.

What you receive when you join the Alpha-1 Study Group

A visit to our leading research clinic at London Bridge

Let our patient service team arrange and pay for all your travel. Get to know our clinicians and meet others with your condition.

Priority consideration for clinical trials

You will be among the first contacted when suitable Alpha-1 studies open.

Free
genetic testing

Find out which form of the disease you have.

A full baseline health assessment

Includes regular follow ups if you join a clinical trial.

Financial compensation

You will be paid for joining the Study Group, with additional payments if you join a clinical trial.

Why join now?

Research into Alpha-1 is entering a period of real momentum. New approaches are being developed, and each new study group participant helps get us closer to potentially transformative new treatments

Contribute directly to advancing Alpha-1 research

Stay informed about new studies and emerging therapies

Give yourself early access to clinical trials that may be suitable for you

Meet our clinicians - we look forward to getting to know you

Enjoy visits to the clinic and meet others with your condition

Help future generations who may also be affected by Alpha-1

What is Alpha-1 Antitrypsin Deficiency?

Alpha-1 Antitrypsin Deficiency (AATD) is a hereditary genetic condition that can affect the lungs and liver.

It occurs when the body produces too little alpha-1 antitrypsin (AAT), a protein that helps protect lung tissue. This shortage can lead to breathlessness, wheezing or chronic cough. In some people, abnormal AAT proteins can build up in the liver, which may cause inflammation or long-term liver damage.

AATD is often under-diagnosed. Genetic testing can confirm whether you have a more severe form of the condition such as Pi*ZZ and can help you access relevant clinical trials.

Register your interest for our Alpha-1 Study Group by completing the form below

If you have previously registered with Trials4us, please call 020 7042 5802 instead of completing this form

Comments from volunteers

Thanks very much to the Volunteer Recruitment Team. I am so excited to be part of this trial. I can’t thank you and your colleagues enough for all your help, professionalism, and kindness.

Steve K

Unbelievable service! They looked after me so well, and I would recommend them to anyone interested in participating in a clinical trial. I want to thank all the staff at trials4us for their continued efforts and for looking after me so well.

Chas

Very impressive. Thank you for taking care of me and for the valuable service you offer.

Joann

Very professional environment in the heart of London to conduct studies that help discover the medicines of the future.

James

Read all reviews

Do you, or someone you know, have Alpha-1 Antitrypsin Deficiency?

If you have been diagnosed with Alpha-1, we would like to hear from you.

What you receive when you join the Alpha-1 Study Group

A visit to our leading research clinic at London Bridge