020 7042 5802 - 9:00am to 5:00pm - Mon to Fri
Recruiting Adults With Atherosclerotic Cardiovascular Disease (ASCVD) And/Or Uncontrolled Hyperlipidaemia
You will receive up to a maximum amount of £40 per visit.
Duration of stay
Process takes 2 weeks with follow ups for 12 months.
Ages
18-70
Location
London Bridge
Gender
Males & Females
Ethnicity
Any
Payment
£40 per visit
Nicotine Users
Eligible
Summary
- We are conducting a patient engagement study, which is a research study that does not include an investigational drug.
- This study aims to help participants with or at high risk for ASCVD and/or uncontrolled hyperlipidaemia decide if they want to participate in and confirm if suitable for future gene editing studies aimed to help lower lipids/cholesterol.
- In this study we are recruiting participants aged 18 to 70 who have or are at high risk to develop atherosclerotic cardiovascular disease (ASCVD) and/or uncontrolled hyperlipidaemia (high levels of bad cholesterol despite taking available treatments). ASCVD is caused by the buildup of fat in the arteries limiting blood flow to organs which leads to heart attack and stroke.
- We will give you a tour of the study unit and conduct a number of clinical tests and assessments to establish your current health status.
- You will be reimbursed for your travel expenses if you take part in this study.
A member of our recruitment team will discuss the patient engagement study with you before your in-person visit to explain the study details and confirm interest.
If you are interested in participating in this patient engagement study:
- You will be asked to attend an in-person visit, during which we will give you a tour of the study unit and perform tests and assessments such as taking your blood, checking your heart and carrying out a physical examination. These tests can be spread over multiple days (if required).
- You will have a follow-up telephone call with the Study Doctor within 2 weeks after the in-person visit to discuss the results of the clinical assessments you have undergone and provide you with the opportunity to ask any questions.
- While taking part in the study, you will receive information on available gene editing clinical trials that may be a good fit for you. If you agree, we will also provide you with a hard copy of a patient information sheet for an upcoming gene editing clinical trial to take home (if available).
- This means the whole process takes approximately 2 weeks, but optional visits can take place for up to 12 months.
- You may be offered an optional additional in-person visit for repeat clinical tests and assessments if there are significant changes to your health, at the Study Doctor’s discretion. In total, you will come to the research unit at least once.
Who can take part?
We will check your eligibility for the patient engagement study using the following criteria:
- You must be a male or female aged between 18 to 70 years (inclusive).
- You must have a known or suspected history of one of the following:
ASCVD and/or severe hypercholesterolemia (high levels of cholesterol in blood) and/or familial hypercholesterolemia (FH) (an inherited condition that causes very high cholesterol levels).
- You must be currently taking a cholesterol-lowering medicine (e.g., statin, ezetimibe, or PCSK9 inhibitor) or have a documented history of side effects to at least one cholesterol-lowering medicine.
- You must have cholesterol levels that remain too high even after taking approved cholesterol lowering medications. You must be able and willing to provide informed consent to participate.
- You must be able and willing to comply with study assessments.
Duration of Stay
The whole process takes approximately 2 weeks, but optional visits can take place for up to 12 months.
Participant Reimbursement
Study participants will be reimbursed for any study-related travel expenses. You will receive up to a maximum amount of £40 per visit. Please ask the study staff for more information.
Location
We are based in London Bridge near both the Underground and overhead train Stations.
Our unit address is: Richmond Pharmacology 1A Newcomen Street (Corner of Newcomen and Borough High Street) London SE1 1YR Please note the postcode will take you 5 minutes down the road from the clinic, I would use the map below as a reference (the clinic is on Borough High St, just up from Tesco and opposite the road from Foxtons)
Dates
Please call a recruitment team member on 020 7042 5800 to discuss study dates, or register to receive a call back.
Approval
The contents of this email have been approved by an ethics committee. Any response to this advertisement will be recorded. Your response will not place you under any obligation to participate in this study.
Ref: C24065_Dec-2024 (email_website_advert text)
Trial code:
C24065
Speak to a member of our Volunteer Recruitment Team
Comments from volunteers
Thanks very much to the Volunteer Recruitment Team. I am so excited to be part of this trial. I can’t thank you and your colleagues enough for all your help, professionalism, and kindness.
Steve K
Unbelievable service! They looked after me so well, and I would recommend them to anyone interested in participating in a clinical trial. I want to thank all the staff at trials4us for their continued efforts and for looking after me so well.
Chas
Very impressive. Thank you for taking care of me and for the valuable service you offer.
Joann
Very professional environment in the heart of London to conduct studies that help discover the medicines of the future.
James
Recruiting people with type 2 diabetes
Get paid $150 for your time in this study
Register now
Duration of stay
You will need to attend an in-person visit, In total, you will come to the research unit at least once.
View trial dates
Ages
18-70
Location
London Bridge
Gender
Males & Females
Ethnicity
Any
Payment
£1,000
Ages
C23017
Smoking Restrictions
Smokers and non-smokers included
Register now
Email us
Call: 020 7042 5800
Study Summary
We are conducting a study for participants with genetically diagnosed alpha-1 antitrypsin deficiency (Alpha 1) who are interested in participating in future gene editing clinical trials.
In this study, we are recruiting participants with Alpha 1 (with a known or suspected PiZZ mutation) aged 18 to 70. We will give you a tour of the clinical trials unit and conduct a number of clinical assessments to establish your current health status.
This study is to help participants with Alpha 1 decide if they want to participate in future gene editing clinical trials.
In this study, we are recruiting participants with Alpha 1 (with a known or suspected PiZZ mutation) aged 18 to 70. We will give you a tour of the clinical trials unit and conduct a number of clinical assessments to establish your current health status.
This study is to help participants with Alpha 1 decide if they want to participate in future gene editing clinical trials.
If you are interested in participating in this patient engagement study
- You will need to attend an in-person visit, we will give you a tour of the clinical trial unit and perform tests to check your general health to obtain a clinical baseline.
- The tests can be spread over multiple days (if required).
- You will have a follow-up call with a doctor a week after the in-person visit.
- This means the whole process takes approximately 1 week.
Who can take part?
We will check your suitability for the clinical trial using the following criteria:
- You are aged between 18 to 70 years (inclusive).
- You must have been diagnosed with alpha-1 antitrypsin deficiency (Alpha 1) (with a known or suspected PiZZ mutation).
- You must be able and willing to provide informed consent.
- You must be willing and able to comply with study assessments.
A full list of do’s and don’ts will be given to you by a member of our recruitment team if you are interested and want to find out more.
Study payment
In recognition of the time and effort involved in taking part in the study, you will receive £150 on completion of the study, provided you comply fully with all the study requirements.
Study dates
Following the completion of your registration form, a member of our recruitment team will contact you via phone and email to inform of the available dates.
Approval
The contents of this email have been approved by an ethics committee. Any response to this advertisement will be recorded. Your response will not place you under any obligation to participate in this trial.
You may be required to remain resident in the unit until resolution of any safety issues, after which you will be discharged from the unit.
Ref: C23017_MAR_2024 (email_website_advert text)
You may be required to remain resident in the unit until resolution of any safety issues, after which you will be discharged from the unit.
Ref: C23017_MAR_2024 (email_website_advert text)
Register now
Speak to a member of our Volunteer Recruitment Team
Call: 020 7042 5800