020 7042 5800 - 9:00am to 5:00pm - Mon to Fri
Duration of stay
You will need to attend an in-person visit, In total, you will come to the research unit at least once.
London Bridge
Males & Females
Smoking Restrictions
Smokers and non-smokers included
Trial Code
C23017 (Cohort 1)
Paid on completion of the study.
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Study summary

We are  We are conducting a study for participants with genetically diagnosed alpha-1 antitrypsin deficiency (Alpha 1) who are interested in participating in future gene editing clinical trials. In this study, we are recruiting participants with Alpha 1 (with a known or suspected PiZZ mutation) aged 18 to 70. We will give you a tour of the clinical trials unit and conduct a number of clinical assessments to establish your current health status. This study is to help participants with Alpha 1 decide if they want to participate in future gene editing clinical trials.

If you are interested in participating in this patient engagement study:-

  • You will need to attend an in-person visit, we will give you a tour of the clinical trial unit and perform tests to check your general health to obtain a clinical baseline.
  • The tests can be spread over multiple days (if required).
  • You will have a follow-up call with a doctor a week after the in-person visit.
  • This means the whole process takes approximately 1 week.
  • In total, you will come to the research unit at least once.
  • During your in-person visit, we will conduct number of assessments. We will take blood, check your heart and carry out a physical examination to check your health. If available, we also will provide you with a hard copy of a patient information sheet for an upcoming gene editing clinical trial to take home.
Register for this trial

Who can take part?

We will check your suitability for the clinical trial using the following criteria:-

  • You are aged between 18 to 70 years (inclusive).
  • You must have been diagnosed with alpha-1 antitrypsin deficiency (Alpha 1) (with a known or suspected PiZZ mutation).
  • You must be able and willing to provide informed consent.
  • You must be willing and able to comply with study assessments.

A full list of do’s and don’ts will be given to you by a member of our recruitment team if you are interested and want to find out more.

Study payment

In recognition of the time and effort involved in taking part in the study, you will receive £150 on completion of the study, provided you comply fully with all the study requirements.

Study dates

Following the completion of your registration form, a member of our recruitment team will contact you via phone and email to inform of the available dates.


The contents of this email have been approved by an ethics committee. Any response to this advertisement will be recorded. Your response will not place you under any obligation to participate in this trial.

You may be required to remain resident in the unit until resolution of any safety issues, after which you will be discharged from the unit.

Ref: C23017_MAR_2024 (email_website_advert text)

Register for this trial
If you would like to speak to a member of our Volunteer Recruitment Team, call us on 020 7042 5800
Register for this clinical trial

Contact our Volunteer Recruitment Team

Ref: C23017 (Cohort 1) - (email_website_advert text)

Comments from volunteers

Unbelievable service! They looked after me so well, and I would recommend them to anyone interested in participating in a clinical trial. I want to thank all the staff at trials4us for their continued efforts and for looking after me so well.


Very impressive. Thank you for taking care of me and for the valuable service you offer.


Very professional environment in the heart of London to conduct studies that help discover the medicines of the future.


The initial process to get accepted on the trials was easy, and the payment was prompt and precise. The staff here at the clinic are lovely, very professional, helpful, and understanding.


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