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Nicotine Restrictions
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This trial will study a potential new treatment for AATD, a genetic disorder that affects the lungs and liver. We are recruiting people who have a specific type of AATD (PiZZ genotype) who are aged over 18 and less than 75.
By taking part, you could potentially help to advance treatment options.
What taking part in this study involves
This clinical trial has two parts. We are currently recruiting for part A. The trial will help us determine how safe and tolerable the trial drug is, how long it stays in the body, and how it affects the body.
- You will need to attend a screening appointment at our London Bridge unit, so we can check whether you’re suitable to take part in the trial. At this appointment, we will perform assessments including checking your heart function and taking blood
- The trial involves a stay of 3 days/2 nights in our London Bridge unit. During your stay, you will receive a single dose of the trial drug as an injection under the skin
- You will then need to attend 10 follow-up visits. From your screening to your last visit, the trial will take approximately 55 weeks in total
Who can take part?
You may be eligible for this clinical trial if:
- You are aged over 18 and less than 75 years old
- You weigh between 45-110 kg and your BMI is between 18-33 kg/m2
- You haven’t smoked or vaped for at least 6 months before screening
- You haven’t received AAT therapy within 30 days prior to screening
- You haven’t had a respiratory tract infection that required treatment within 8 weeks prior to dosing (receiving the trial drug)
Please note there are additional study criteria. A full list will be given to you by a member of our recruitment team if you are interested.
You could receive up to £6,625
You will be paid £6,625 on completion of the clinical trial, provided that you comply fully with all the requirements. If we invite you to attend extra visits, this amount will be adjusted pro-rata.
Trial dates
Call us on 020 7042 5802 for information regarding trial dates, on Mon-Fri between 09h00 and 17h00.
Email: volunteer@richmondpharmacology.com
Approval
Any response to this advertisement will be recorded. Your response will not place you under and obligation to participate in this study.
Ref: Ref: C25018_Feb-2026 (email_website_advert text)
