Trial Code
Ages
Location
Gender
Ethnicity
Payment
Nicotine Restrictions
Duration of stay
Clinical trial summary
- The clinical trial involves having an injection(s) under the skin in your abdomen.
- Following dosing, there will be several assessments that will help us to collect information to determine the safety and tolerability of the investigational drug, how long it stays in your body, and how it affects your body.
- You will receive a single injection of the investigational drug or placebo.
- You will be paid for your time if you take part in this clinical trial.
If you are interested in participating in the trial:
- You will need to attend a screening appointment so we can check if you are suitable to take part in the trial. At this appointment, we will perform several assessments, including but not limited to taking blood, checking your heart function, and carrying out a physical examination. Screening will be conducted over one day or may be divided into more than one day if necessary.
- If results from your screening appointment show you are suitable for the trial, you will be invited to take part.
- There will be an in-house stay of approximately 4 days/ 3 nights in our clinical research unit. You will be admitted in the unit the day before dosing (Day -1).
- During your stay, on Day 1 you will receive a single injection under the skin in your abdomen and be closely observed by medically qualified staff. We will also conduct a number of assessments (like those we did at screening) to check how safe and tolerable the trial drug is, how long the drug remains in your body and how it affects your body.
Who can take part
We will check your suitability for the study using the following criteria:
- You are a male or female of non-childbearing potential aged between 18 and 45 years old(inclusive).
- You weigh over 50 kg and have a BMI between 18 and 25 kg/m2, inclusive, at screening.
- You must be healthy.
- You must not have a history of any bleeding and/or blood clots.
- You must not have had any major surgery within 6 months before Screening.
- You must not have history of spontaneous bleeding (e.g., nosebleeds, haemorrhoidal bleeding) within the last 6 months before Screening.
- You must not have used blood thinning medications (e.g., anticoagulants, antiplatelets) within 30 days before Day 1 (dosing).
- You must not have used tobacco and/or nicotine-containing products within 6 months prior to Day 1 (dosing).
- You must not have participated in a clinical trial with an investigational drug within the last 90 days before dosing.
- Male participants with female partners of childbearing potential must be willing to use appropriate barrier contraception for the duration of the trial and their female partners must also use highly effective contraception.
A member of our recruitment team will give you a full list of do’s and don’ts if you are interested.
Payment
In recognition of the time involved in taking part in the trial, you will receive £5,025* on completion of the clinical trial, provided you comply fully with all the clinical trial requirements (£3,350 clinical trial payment and £1,675 compliance bonus). This amount is based on the anticipated clinical trial plan and will be adjusted pro-rata (i.e. same amount of money paid per unit of time), should we invite you to attend extra visits.
*£75 of your study payment will be for the Screening visit.
Dates
The trial will take place on one of the below time periods, for your in-house stay of 3 days – you will only need to stay overnight for one of these periods. You will then also be required to attend up to 11 follow up sessions. Dates for follow up visits will be discussed with you by our team.
- 09th – 12th February 2026
- 16th - 19th February 2026
After your stay with us, you will be required to return for at least 12 follow-up visits on the following days: 8, 15, 22, 29, 36, 43, 50, 57, 85, 113, 141 and 180. You may have to attend two additional follow-up visits on days 270 and 360, depending on the results of the blood tests of each participant in your study group. The whole process may take approximately 13 months from your screening visit through to your final visit. In total, you may have to attend the unit on potentially 16 occasions (including the additional follow-up visits).
Contact Us for More Information
Email: volunteer@richmondpharmacology.com
Call us: Mon - Fri between 09h00 and 17h00 on +44 (0) 207 042 5802 to speak to a member of our Volunteer Recruitment Team.
Approval
The contents of this document have been approved by an Ethics Committee. Any response to this advertisement will be recorded. Your response will not place you under any obligation to participate in this trial.
Ref: C24027_Oct-2025 (email_website_advert text)
